Zosteriform Dissemination of Molluscum Contagiosum Infection Diagnosed in an Immunocompetent Girl: A Rare Clinical Presentation

Molluscum contagiosum (MC) is a benign, self-limiting infectious lesion that primarily affects children and young adults, especially those with immunodeficiency. MC is caused by a poxvirus from the Molluscipoxvirus genus of the Poxviridae family. Diagnosis is mainly clinical, with lesions presenting as dome-shaped, spherical, solid, flesh-colored, pearly papules with central umbilication. MC commonly appears on the limbs, face, trunk, and axillary regions. The differential diagnosis includes inflammatory, infectious, and neoplastic causes, varying by age and immunological condition. This case report presents a rare zosteriform distribution of MC infection in an immunocompetent girl, a presentation described only twice in medical literature. The unusual distribution resulted from scratching, a process known as the Koebner phenomenon (pseudo-koebnerization).

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Journal
Clinical Case Reports
Published
2025-03-01
DOI
https://doi.org/10.1002/ccr3.70301
Primary Topic
Poxvirus research and outbreaks
Type
article
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article

Zosteriform Dissemination of Molluscum Contagiosum Infection Diagnosed in an Immunocompetent Girl: A Rare Clinical Presentation

Zuheir Alshehabi, Lina Al‐Soufi, Mohammad Adi, Aya Marashli
Clinical Case Reports
Poxvirus research and outbreaks
article

Zosteriform Dissemination of Molluscum Contagiosum Infection Diagnosed in an Immunocompetent Girl: A Rare Clinical Presentation

Zuheir Alshehabi, Lina Al‐Soufi, Mohammad Adi, Aya Marashli
article en

Abstract

Molluscum contagiosum (MC) is a benign, self-limiting infectious lesion that primarily affects children and young adults, especially those with immunodeficiency. MC is caused by a poxvirus from the Molluscipoxvirus genus of the Poxviridae family. Diagnosis is mainly clinical, with lesions presenting as dome-shaped, spherical, solid, flesh-colored, pearly papules with central umbilication. MC commonly appears on the limbs, face, trunk, and axillary regions. The differential diagnosis includes inflammatory, infectious, and neoplastic causes, varying by age and immunological condition. This case report presents a rare zosteriform distribution of MC infection in an immunocompetent girl, a presentation described only twice in medical literature. The unusual distribution resulted from scratching, a process known as the Koebner phenomenon (pseudo-koebnerization).

Clinical Case ReportsVol. 13(3)
Latakia University (SY), Damascus University (SY)
Openalex Percentile: Top 95%
Poxvirus research and outbreaks
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Zosteriform Dissemination of Molluscum Contagiosum Infection Diagnosed in an Immunocompetent Girl: A Rare Clinical Presentation — Zuheir Alshehabi, Lina Al‐Soufi, et al. · Clinical Case Reports (2025) | TGRS Research Map | TGRS