Visual outcome including visual field defects after treatment of paediatric optic pathway glioma: A nationwide cohort study

In this study, long-term binocular severe VI or blindness appeared in almost one in five patients and in one in three eyes after diverse treatment for paediatric OPG. Visual field data were available in only one in two children; VF defects were present in four out of five eyes. Children starting therapy under the age of 2 years were particularly at risk for long-term severe VI or blindness. Future prospective studies need to include VF analysis as an outcome parameter and should analyse treatment effects on both monocular and binocular BCVA.

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Publication Details

Journal
Acta Ophthalmologica
Published
2025-03-08
DOI
https://doi.org/10.1111/aos.17476
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
0.00

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article

Visual outcome including visual field defects after treatment of paediatric optic pathway glioma: A nationwide cohort study

Annabel L. W. Groot, Carlien A. M. Bennebroek, Peerooz Saeed, Irene C. Notting et al.
Acta Ophthalmologica
Neurofibromatosis and Schwannoma Cases
article

Visual outcome including visual field defects after treatment of paediatric optic pathway glioma: A nationwide cohort study

Annabel L. W. Groot, Carlien A. M. Bennebroek, Peerooz Saeed, Irene C. Notting, Sjoukje E. Loudon, Giorgio L. Porro, Antoinette Y. N. Schouten‐van Meeteren, Pim de Graaf, Maria M. van Genderen, J. van Zwol, Maartje C. Montauban van Swijndregt, Jan Willem R. Pott, Arlette J. van Sorge, Noël J.C. Bauer
article en

Abstract

In this study, long-term binocular severe VI or blindness appeared in almost one in five patients and in one in three eyes after diverse treatment for paediatric OPG. Visual field data were available in only one in two children; VF defects were present in four out of five eyes. Children starting therapy under the age of 2 years were particularly at risk for long-term severe VI or blindness. Future prospective studies need to include VF analysis as an outcome parameter and should analyse treatment effects on both monocular and binocular BCVA.

Acta OphthalmologicaVol. 103(6)
University Medical Center Groningen (NL), Radboud University Nijmegen (NL), University of Groningen (NL), Leiden University Medical Center (NL), Erasmus MC (NL), Radboud University Medical Center (NL), University Medical Center Utrecht (NL), Maastricht University (NL), Princess Máxima Center (NL), Visio (NL), Amsterdam University Medical Centers (NL), Bartiméus (NL), Hersenstichting (NL), Cancer Center Amsterdam (NL), Vrije Universiteit Amsterdam (NL), University of Amsterdam (NL)
ODAS Stichting
Good health and well-being
Openalex Percentile: Top 93%
Neurofibromatosis and Schwannoma Cases
DOIOpen Access PDFOpenAlex
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