<scp>ITGAM</scp> Upregulation in Acute Myeloid Leukemia Leads to Poor Prognosis Associated With Infiltration of Inhibitory Innate Immune Cells

These findings suggest that ITGAM could serve as a valuable prognostic biomarker in AML, reflecting an adverse prognosis associated with enhanced infiltration of immunosuppressive innate immune cells.

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Publication Details

Journal
International Journal of Laboratory Hematology
Published
2025-03-07
DOI
https://doi.org/10.1111/ijlh.14444
Primary Topic
Immune cells in cancer
Type
article
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article

ITGAM Upregulation in Acute Myeloid Leukemia Leads to Poor Prognosis Associated With Infiltration of Inhibitory Innate Immune Cells

Chenchen Qin, Chang Su, Zhenhai Zhou, Dong Zheng et al.
International Journal of Laboratory Hematology
Immune cells in cancer
article

ITGAM Upregulation in Acute Myeloid Leukemia Leads to Poor Prognosis Associated With Infiltration of Inhibitory Innate Immune Cells

Chenchen Qin, Chang Su, Zhenhai Zhou, Dong Zheng, Xiu‐Zhen Tong
article en

Abstract

These findings suggest that ITGAM could serve as a valuable prognostic biomarker in AML, reflecting an adverse prognosis associated with enhanced infiltration of immunosuppressive innate immune cells.

International Journal of Laboratory HematologyVol. 47(3)
Sun Yat-sen University (CN), The First Affiliated Hospital, Sun Yat-sen University (CN)
No poverty
Openalex Percentile: Top 95%
Immune cells in cancer
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