Use of Tranexamic Acid in Head and Neck Free Flap Reconstruction
Patients who received TXA demonstrated decreased perioperative transfusion after head and neck free flap reconstruction with no increase in flap vascular compromise or major thromboembolic events. Implementation of our protocol to larger cohorts and randomized controlled trials could help identify an optimal dosing regimen and demonstrate long-term efficacy.
Authors
- Michael L. Gimbel (ORCID: https://orcid.org/0000-0001-6709-3801)
- Arash Samadi (ORCID: https://orcid.org/0000-0003-4367-6409)
- Vu T. Nguyen (ORCID: https://orcid.org/0009-0003-0767-7241)
- Fuat Barış Bengür (ORCID: https://orcid.org/0000-0002-6036-3458)
- Kevin J. Contrera (ORCID: https://orcid.org/0000-0002-2570-1706)
- Mario G. Solari (ORCID: https://orcid.org/0000-0001-9366-521X)
- Joshua D. Smith (ORCID: https://orcid.org/0000-0002-2076-7589)
- Mark Kubik (ORCID: https://orcid.org/0000-0002-8646-9920)
- Michael S. Hu (ORCID: https://orcid.org/0000-0002-5755-910X)
- Rula Mualla
- Shaum Sridharan (ORCID: https://orcid.org/0000-0001-6049-1508)
- Matthew E. Spector (ORCID: https://orcid.org/0000-0001-7646-6075)
- Micah K. Harris (ORCID: https://orcid.org/0009-0004-5036-8919)
- Olivier Bourguillon
Institutions
- University of Pittsburgh Medical Center (US)
Publication Details
- Journal
- Microsurgery
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/micr.70046
- Citations
- 2
- Primary Topic
- Reconstructive Surgery and Microvascular Techniques
- Type
- article
- Field-Weighted Citation Impact
- 4.01