Systemic Anti‐Inflammatory Effects of Isotretinoin: Evaluation of Red Cell Distribution Width to Lymphocyte and Platelet Ratios as New Hematological Markers and Clinical Outcomes in Acne Vulgaris

This study highlights the systemic immunomodulatory effects of isotretinoin, particularly the significant changes in RDW-derived ratios, suggesting their potential as novel inflammatory markers. These findings reinforce the broader effects of isotretinoin beyond sebaceous gland suppression and support its role in the regulation of systemic inflammation.

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Publication Details

Journal
Journal of Cosmetic Dermatology
Published
2025-03-01
DOI
https://doi.org/10.1111/jocd.70108
Citations
4
Primary Topic
Acne and Rosacea Treatments and Effects
Type
article
Field-Weighted Citation Impact
8.02
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article

Systemic Anti‐Inflammatory Effects of Isotretinoin: Evaluation of Red Cell Distribution Width to Lymphocyte and Platelet Ratios as New Hematological Markers and Clinical Outcomes in Acne Vulgaris

Gözde Ulutaş Demirbaş, Zeynep Gizem Kaya İslamoğlu, Abdullah Demirbaş, Esin Diremsizoğlu
4 citations
Journal of Cosmetic Dermatology
Acne and Rosacea Treatments and Effects
8.02
article

Systemic Anti‐Inflammatory Effects of Isotretinoin: Evaluation of Red Cell Distribution Width to Lymphocyte and Platelet Ratios as New Hematological Markers and Clinical Outcomes in Acne Vulgaris

Gözde Ulutaş Demirbaş, Zeynep Gizem Kaya İslamoğlu, Abdullah Demirbaş, Esin Diremsizoğlu
article en
4 citations

Abstract

This study highlights the systemic immunomodulatory effects of isotretinoin, particularly the significant changes in RDW-derived ratios, suggesting their potential as novel inflammatory markers. These findings reinforce the broader effects of isotretinoin beyond sebaceous gland suppression and support its role in the regulation of systemic inflammation.

Journal of Cosmetic DermatologyVol. 24(3)
Konya Eğitim ve Araştırma Hastanesi (TR)
Openalex Percentile: Top 3%
Acne and Rosacea Treatments and Effects
8.02
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