Left parietal structural connectivity mediates typical and atypical language laterality in temporal lobe epilepsy
Language-related left parietal lobe connections were critical both for maintaining typical left hemisphere-biased language processing in the temporal lobe and for the formation of noncanonical, potentially adaptive language processing asymmetries in the frontal and parietal lobes. Assessments of the laterality and integrity of language skills in left temporal lobe epilepsy will require modeling white matter structural influences.
Authors
- Michael R. Sperling (ORCID: https://orcid.org/0000-0003-0708-6006)
- Joseph I. Tracy (ORCID: https://orcid.org/0000-0001-5260-3290)
- Ankeeta Ankeeta
- Xiaosong He
- Salvatore Citro (ORCID: https://orcid.org/0000-0001-5222-6501)
- Sam S. Javidi
- Qirui Zhang (ORCID: https://orcid.org/0000-0002-3520-9336)
- Yolanda Kry
Institutions
- University of Science and Technology of China (CN)
- Thomas Jefferson University (US)
Publication Details
- Journal
- Epilepsia
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1111/epi.18298
- Citations
- 1
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- National Institutes of Health