Subdivided Historical Data to Assess Replicability of the Rat Embryo‐Fetal Developmental Toxicity Study
The observed 5%-7% differences between these idealized replicates may represent the lower bound for acceptable variability when merging replicate data sets. This work lays the groundwork for more robust evaluations of replicability in EFDT studies and may inform future regulatory guidance.
Authors
- L. David Wise (ORCID: https://orcid.org/0000-0002-2280-0725)
Publication Details
- Journal
- Birth Defects Research
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/bdr2.2461
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 0.00