Acid–base implications of the Gibbs-Donnan effect during continuous veno-venous hemofiltration
These in-vitro and in-vivo studies demonstrate that albumin linearly affects the sieving coefficient of ions, increasing the strong ion difference of plasma water during its passage through the filter and thus having a systemic alkalizing effect.
Authors
- Beatrice Brunoni (ORCID: https://orcid.org/0009-0002-3110-5967)
- Francesca Mulazzani (ORCID: https://orcid.org/0009-0003-8425-6117)
- Stefania Paccagnini
- Francesco Zadek (ORCID: https://orcid.org/0000-0002-2377-3992)
- Thomas Länger (ORCID: https://orcid.org/0000-0002-9725-8520)
- Roberto Fumagalli (ORCID: https://orcid.org/0000-0003-0398-1329)
- Maria Luisa De Angelis
- Irene Sironi
Institutions
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- University of Milano-Bicocca (IT)
Publication Details
- Journal
- Journal of Nephrology
- Published
- 2025-03-09
- DOI
- https://doi.org/10.1007/s40620-025-02238-0
- Citations
- 2
- Primary Topic
- Renal function and acid-base balance
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Università degli Studi di Milano-Bicocca