Etiology and Antimicrobial Resistance of Culture-Positive Infections in Ugandan Infants: A Cohort Study of 7000 Neonates and Infants
Our study demonstrates high levels of antimicrobial resistance and inpatient mortality from neonatal sepsis in the first months of life in Uganda. This underscores the pressing need for revised, context-specific antimicrobial treatment guidelines that account for the evolving landscape of antimicrobial resistance in neonatal sepsis.
Authors
- Joseph Peacock (ORCID: https://orcid.org/0000-0002-8767-7377)
- Alexander Amone (ORCID: https://orcid.org/0000-0001-5920-281X)
- Ritah Namugumya
- Agnes Ssali (ORCID: https://orcid.org/0000-0003-4801-0411)
- Tim Old (ORCID: https://orcid.org/0000-0003-2564-2555)
- Carol Nanyunja (ORCID: https://orcid.org/0000-0003-3684-4267)
- Paul T. Heath (ORCID: https://orcid.org/0000-0002-7540-7433)
- Valerie Tusubira (ORCID: https://orcid.org/0000-0002-3395-8755)
- Daniel Shelley
- Geraldine O’Hara (ORCID: https://orcid.org/0000-0002-1922-9492)
- Hannah G Davies (ORCID: https://orcid.org/0000-0002-9064-0874)
- Vicki Chalker
- Phiona Nalubega
- Juliet Nsimire Sendagala
- Caitlin Farley (ORCID: https://orcid.org/0009-0006-5309-2991)
- Mary Kyohere
- Lauren Hookham (ORCID: https://orcid.org/0000-0001-9703-655X)
- Kirsty Le Doaré (ORCID: https://orcid.org/0000-0002-5104-085X)
- Konstantinos Karampatsas (ORCID: https://orcid.org/0000-0002-5313-9482)
- Abdelmajid Djennad (ORCID: https://orcid.org/0000-0002-4830-0331)
- Godfrey Matovu
- Melanie Etti (ORCID: https://orcid.org/0000-0002-3265-635X)
- Moses Musooko
- Philippa Musoke
- Edward Portal (ORCID: https://orcid.org/0000-0003-2142-3443)
- Madeleine Cochet (ORCID: https://orcid.org/0000-0002-0436-4843)
- Maxensia Owor
- Cleophas Komugisha
- Scott Richard Beach (ORCID: https://orcid.org/0000-0001-7513-9515)
- Musa Sekikubo (ORCID: https://orcid.org/0000-0002-7335-9650)
- Patience Atuhaire (ORCID: https://orcid.org/0000-0002-2662-0756)
- Margaret Sewegaba
- Tobius Mutabazi (ORCID: https://orcid.org/0000-0001-6711-1416)
- Katie Cowie
- Stephen D. Bentley (ORCID: https://orcid.org/0000-0001-8094-3751)
- Janet Seeley (ORCID: https://orcid.org/0000-0002-0583-5272)
- Merryn Voysey (ORCID: https://orcid.org/0000-0001-6324-6559)
- Annettee Nakimuli (ORCID: https://orcid.org/0000-0003-2806-0243)
- O. Brad Spiller (ORCID: https://orcid.org/0000-0002-9117-6911)
- Emilie Karafillakis (ORCID: https://orcid.org/0000-0001-8648-906X)
- Pooja Ravji (ORCID: https://orcid.org/0000-0002-2878-5538)
- R.W. Parks
- Ellie Duckworth
- Rose Azuba
- Sam Kipyeko
- Amusa Wamawobe (ORCID: https://orcid.org/0000-0001-7503-6778)
- Agnes Nyamaizi
- Amusa Wamawobe
- Christine Najuka
- Richard Katungye
Institutions
- St George's, University of London (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- University of Oxford (GB)
- London School of Hygiene & Tropical Medicine (GB)
- MUJHU Research Collaboration (UG)
- Institute of Infection and Immunity (CA)
- Makerere University (UG)
- Cardiff University (GB)
- Uganda Virus Research Institute (UG)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1093/ofid/ofae629
- Citations
- 5
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Bill and Melinda Gates Foundation
- University of London
- St. George's, University of London