Rapid Point-of-care Testing to Inform Intrapartum Treatment of Group B <i>Streptococcus</i>–Colonized Women in Uganda
The results of this study demonstrate high sensitivity and specificity of the HG GBS LAMP assay for the detection of GBS rectovaginal colonization in our setting. Given its rapid turnaround time, the HG GBS LAMP assay could appropriately be used to screen women for GBS rectovaginal colonization during labor to enable provision of intrapartum antibiotic prophylaxis.
Authors
- Joseph Peacock (ORCID: https://orcid.org/0000-0002-8767-7377)
- Alexander Amone (ORCID: https://orcid.org/0000-0001-5920-281X)
- Ritah Namugumya
- Agnes Ssali (ORCID: https://orcid.org/0000-0003-4801-0411)
- Tim Old (ORCID: https://orcid.org/0000-0003-2564-2555)
- Carol Nanyunja (ORCID: https://orcid.org/0000-0003-3684-4267)
- Paul T. Heath (ORCID: https://orcid.org/0000-0002-7540-7433)
- Valerie Tusubira (ORCID: https://orcid.org/0000-0002-3395-8755)
- Geraldine O’Hara (ORCID: https://orcid.org/0000-0002-1922-9492)
- Hannah G Davies (ORCID: https://orcid.org/0000-0002-9064-0874)
- Vicki Chalker
- Phiona Nalubega
- Juliet Nsimire Sendagala
- Caitlin Farley (ORCID: https://orcid.org/0009-0006-5309-2991)
- Mary Kyohere
- Lauren Hookham (ORCID: https://orcid.org/0000-0001-9703-655X)
- Kirsty Le Doaré (ORCID: https://orcid.org/0000-0002-5104-085X)
- Konstantinos Karampatsas (ORCID: https://orcid.org/0000-0002-5313-9482)
- Abdelmajid Djennad (ORCID: https://orcid.org/0000-0002-4830-0331)
- Godfrey Matovu
- Melanie Etti (ORCID: https://orcid.org/0000-0002-3265-635X)
- Moses Musooko
- Philippa Musoke
- Edward Portal (ORCID: https://orcid.org/0000-0003-2142-3443)
- Madeleine Cochet (ORCID: https://orcid.org/0000-0002-0436-4843)
- Maxensia Owor
- Cleophas Komugisha
- Scott Richard Beach (ORCID: https://orcid.org/0000-0001-7513-9515)
- Musa Sekikubo (ORCID: https://orcid.org/0000-0002-7335-9650)
- Patience Atuhaire (ORCID: https://orcid.org/0000-0002-2662-0756)
- Margaret Sewegaba
- Tobius Mutabazi (ORCID: https://orcid.org/0000-0001-6711-1416)
- Katie Cowie
- Ruth Parks (ORCID: https://orcid.org/0000-0003-3832-7431)
- Stephen D. Bentley (ORCID: https://orcid.org/0000-0001-8094-3751)
- Janet Seeley (ORCID: https://orcid.org/0000-0002-0583-5272)
- Merryn Voysey (ORCID: https://orcid.org/0000-0001-6324-6559)
- Annettee Nakimuli (ORCID: https://orcid.org/0000-0003-2806-0243)
- Dan R Shelley
- O. Brad Spiller (ORCID: https://orcid.org/0000-0002-9117-6911)
- Emilie Karafillakis (ORCID: https://orcid.org/0000-0001-8648-906X)
- Pooja Ravji (ORCID: https://orcid.org/0000-0002-2878-5538)
- Ellie Duckworth
- Rose Azuba
- Sam Kipyeko
- Amusa Wamawobe
- Christine Najuka
- Richard Katungye
- Agnes Nyamaizi
Institutions
- St George's, University of London (GB)
- MUJHU Research Collaboration (UG)
- Makerere University (UG)
- Uganda Virus Research Institute (UG)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1093/ofid/ofae605
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bill and Melinda Gates Foundation