Incidence of Hypercalcemia and Vertebral Fractures Following Denosumab Withdrawal in Lung Cancer Patients: A Longitudinal Cohort Study

Patients with bony-metastatic lung cancer, especially post-menopausal women, are at risk of fractures and calcium abnormalities after DMAb discontinuation, suggesting that DMAb withdrawal effect may also be present in the oncological setting. A close follow-up and careful monitoring during and after discontinuation of DMAb is necessary.

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Publication Details

Journal
Journal of Bone Metabolism
Published
2025-02-28
DOI
https://doi.org/10.11005/jbm.24.803
Citations
4
Primary Topic
Bone health and treatments
Type
article
Field-Weighted Citation Impact
4.18
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article

Incidence of Hypercalcemia and Vertebral Fractures Following Denosumab Withdrawal in Lung Cancer Patients: A Longitudinal Cohort Study

Marta Villanova, Sharon H. Chou, Le Min
4 citations
Journal of Bone Metabolism
Bone health and treatments
4.18
article

Incidence of Hypercalcemia and Vertebral Fractures Following Denosumab Withdrawal in Lung Cancer Patients: A Longitudinal Cohort Study

Marta Villanova, Sharon H. Chou, Le Min
article en
4 citations

Abstract

Patients with bony-metastatic lung cancer, especially post-menopausal women, are at risk of fractures and calcium abnormalities after DMAb discontinuation, suggesting that DMAb withdrawal effect may also be present in the oncological setting. A close follow-up and careful monitoring during and after discontinuation of DMAb is necessary.

Journal of Bone MetabolismVol. 32(1)
Brigham and Women's Hospital (US), Harvard University (US)
Good health and well-being
Openalex Percentile: Top 6%
Bone health and treatments
4.18
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