Integrated Analysis of Ferroptosis and Immune Infiltration in Ulcerative Colitis Based on Bioinformatics
In summary, this study identified three key genes related to UC ferroptosis and immunity, namely <i>DUOX2, IDO1</i> and <i>LCN2</i>. These findings suggest that immune infiltration plays an important role in UC caused by ferroptosis, and that there is mutual regulation between UC and immune-infiltrated cells. Our research revealed the potential application of immune and ferroptosis in the diagnosis, treatment and prognosis of UC, providing new strategies for clinical management.
Authors
- Weitao Hu
- Daxing Cai
- Yanliang Cai (ORCID: https://orcid.org/0000-0002-5694-3708)
- Taiyong Fang (ORCID: https://orcid.org/0000-0002-2378-3234)
- Xiaoqing Chen (ORCID: https://orcid.org/0000-0002-1907-8954)
Institutions
- Fujian Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/jir.s501651
- Citations
- 8
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 12.15