Analisis In Silico Senyawa Curcuma xanthorrhiza dan Moringa oleifera sebagai Kandidat Antiinflamasi

Inflammation is the body's immune response to pathogens, tissue injury, or exposure to toxic substances. The search for effective anti-inflammatory agents remains a key focus in pharmaceutical and healthcare research. Temulawak (Curcuma xanthorrhiza) and Moringa (Moringa oleifera) have been widely used in traditional medicine due to their bioactive compounds with potential anti-inflammatory effects. This study aims to evaluate the molecular interactions between curcumin from temulawak, as well as quercetin and kaempferol from moringa, against inflammatory targets using an in silico approach through molecular docking and molecular dynamics simulations.

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Publication Details

Journal
Journal Syifa Sciences and Clinical Research
Published
2025-02-03
DOI
https://doi.org/10.37311/jsscr.v7i1.30385
Primary Topic
Moringa oleifera research and applications
Type
article
Field-Weighted Citation Impact
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article

Analisis In Silico Senyawa Curcuma xanthorrhiza dan Moringa oleifera sebagai Kandidat Antiinflamasi

Okta Nursanti, Lusi Nursilawati Syamsi, Syamsudin Syamsudin, Rahmatul Qodriah et al.
Journal Syifa Sciences and Clinical Research
Moringa oleifera research and applications
article

Analisis In Silico Senyawa Curcuma xanthorrhiza dan Moringa oleifera sebagai Kandidat Antiinflamasi

Okta Nursanti, Lusi Nursilawati Syamsi, Syamsudin Syamsudin, Rahmatul Qodriah, Wahyu Widowati, Esti Mumpuni
article en

Abstract

Inflammation is the body's immune response to pathogens, tissue injury, or exposure to toxic substances. The search for effective anti-inflammatory agents remains a key focus in pharmaceutical and healthcare research. Temulawak (Curcuma xanthorrhiza) and Moringa (Moringa oleifera) have been widely used in traditional medicine due to their bioactive compounds with potential anti-inflammatory effects. This study aims to evaluate the molecular interactions between curcumin from temulawak, as well as quercetin and kaempferol from moringa, against inflammatory targets using an in silico approach through molecular docking and molecular dynamics simulations.

Journal Syifa Sciences and Clinical ResearchVol. 7(1)
Universitas 17 Agustus 1945 Jakarta (ID), Indonesia Defense University (ID)
Openalex Percentile: Top 97%
Moringa oleifera research and applications
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