Ellagitannins (Ellagic Acid, Urolithin A, Urolithin B) Inhibit the Catalytic Activity of Human Recombinant Metalloproteinase 9

Our results showed the promising inhibitory potential of EA, Uro B, and Uro A to affect the catalytic activity of the MMP-9 enzyme and also confirmed the fibronectin domain as a potential site for drug design against MMP-9.

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Publication Details

Journal
Iranian journal of pharmaceutical research
Published
2025-03-09
DOI
https://doi.org/10.5812/ijpr-148332
Primary Topic
Pomegranate: compositions and health benefits
Type
article
Field-Weighted Citation Impact
0.00
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article

Ellagitannins (Ellagic Acid, Urolithin A, Urolithin B) Inhibit the Catalytic Activity of Human Recombinant Metalloproteinase 9

Leila Sadeghi, Gholamreza Dehghan, Nigar Houssein-Zadeh
Iranian journal of pharmaceutical research
Pomegranate: compositions and health benefits
article

Ellagitannins (Ellagic Acid, Urolithin A, Urolithin B) Inhibit the Catalytic Activity of Human Recombinant Metalloproteinase 9

Leila Sadeghi, Gholamreza Dehghan, Nigar Houssein-Zadeh
article en

Abstract

Our results showed the promising inhibitory potential of EA, Uro B, and Uro A to affect the catalytic activity of the MMP-9 enzyme and also confirmed the fibronectin domain as a potential site for drug design against MMP-9.

Iranian journal of pharmaceutical researchVol. 24(1)
University of Tabriz (IR)
Openalex Percentile: Top 95%
Pomegranate: compositions and health benefits
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Ellagitannins (Ellagic Acid, Urolithin A, Urolithin B) Inhibit the Catalytic Activity of Human Recombinant Metalloproteinase 9 — Leila Sadeghi, Gholamreza Dehghan, et al. · Iranian journal of pharmaceutical research (2025) | TGRS Research Map | TGRS