Systematic transcriptome-wide analysis and validation of tributyltin-induced differential changes in the liver with sex-specific effects
Our study highlights significant sex-dependent differences in TBT-induced hepatotoxicity and identifies STAT3 as a critical mediator in male liver cells, providing a novel perspective on the toxicology of TBT.
Authors
- 信彦 古谷 (ORCID: https://orcid.org/0000-0003-3979-3151)
- Pengchen Chen
- Yaping Niu
- Ran Wei (ORCID: https://orcid.org/0009-0007-2395-1692)
- Wenyue Yang (ORCID: https://orcid.org/0000-0002-0446-6567)
- Ziyang Ding
- Yanting Liang
- Pan Huang (ORCID: https://orcid.org/0000-0002-9149-4979)
- Wei Wang (ORCID: https://orcid.org/0000-0001-5401-3331)
- Jinyan Wang
- Sisi Wang (ORCID: https://orcid.org/0000-0002-8686-981X)
- Mingjun Shi (ORCID: https://orcid.org/0000-0002-5927-5493)
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Guiyang Medical University (CN)
- Guangxi Medical University (CN)
- Wenzhou Medical University (CN)
- Southern University of Science and Technology (CN)
- Foshan Maternity and Child Health Care Hospital (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Changzhou University (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.ecoenv.2025.117995
- Citations
- 1
- Primary Topic
- Marine Biology and Environmental Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 1.15