Comprehensive Characterization of Innate and Adaptive Immune Profiles in the Pediatric COVID-19 Convalescent Phase
In the short-term following infection, COVID-19-recovered patients show persistent activation profiles in phagocytes, T-cell subtypes and natural killer cells. Meanwhile, increased production of lymphocytes, TRECs and naive T cells suggests immune response recovery, even in immunosuppressed patients and children with comorbidities. The clinical implications of these findings should be further studied.
Authors
- Olivia Mari Matsuo (ORCID: https://orcid.org/0000-0002-7971-1168)
- Priscila Suguita (ORCID: https://orcid.org/0000-0002-6212-5058)
- Fernanda Andrade Macaferri da Fonseca (ORCID: https://orcid.org/0000-0002-5095-7471)
- Clóvis A. Silva (ORCID: https://orcid.org/0000-0001-9250-6508)
- Maria Fernanda Bádue Pereira (ORCID: https://orcid.org/0000-0001-8844-8245)
- Vera Bain (ORCID: https://orcid.org/0000-0002-5290-6897)
- Thais de Toledo Fink
- Andréia Rangel-Santos (ORCID: https://orcid.org/0000-0002-0577-1117)
- Patrícia Palmeira (ORCID: https://orcid.org/0000-0002-6268-8141)
- Guilherme S Gonçalves (ORCID: https://orcid.org/0000-0002-8946-7306)
- Fernanda Martins (ORCID: https://orcid.org/0000-0001-5233-1926)
- Nadia Litvinov (ORCID: https://orcid.org/0000-0002-4410-2450)
- Simone Correa‐Silva (ORCID: https://orcid.org/0000-0002-4511-412X)
- Camilla Astley (ORCID: https://orcid.org/0000-0003-4033-2432)
- Arthur Eduardo Fernandes Ferreira
- Magda Maria Sales Carneiro-Sampaio (ORCID: https://orcid.org/0000-0002-1924-4043)
- Heloísa Helena de Sousa Marques (ORCID: https://orcid.org/0000-0002-0940-7793)
- Yingying Zheng (ORCID: https://orcid.org/0000-0003-3747-0930)
- José Climério de Moura Ferreira
- Isabela Silva-Avelar
Institutions
- Universidade de São Paulo (BR)
- Hospital de Clínicas (UY)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1097/inf.0000000000004713
- Citations
- 2
- Primary Topic
- Kawasaki Disease and Coronary Complications
- Type
- article
- Field-Weighted Citation Impact
- 4.01