High Mortality Due to Pneumococcal Meningitis in Children With Sickle Cell Disease: A French Multicenter Observational Study From 2001 to 2021
The occurrence of pneumococcal meningitis in children with SCD during the pneumococcal conjugate vaccines era was associated with a high case-fatality rate and a predominance of nonvaccine serotypes. The implementation of new serotype-expanded PCV may have a potentially positive impact on this vulnerable population.
Authors
- Emmanuelle Varon (ORCID: https://orcid.org/0000-0002-3043-2838)
- Mariane De Montalembert
- Guillaume Costa (ORCID: https://orcid.org/0009-0008-9913-459X)
- Naïm Ouldali (ORCID: https://orcid.org/0000-0003-4996-9640)
- Marine Houlier
- Étienne Carbonnelle (ORCID: https://orcid.org/0000-0003-4354-5900)
- Annie Kamdem
- Marie‐Hélène Odièvre (ORCID: https://orcid.org/0000-0001-7986-2014)
- Slimane Allali (ORCID: https://orcid.org/0000-0001-7068-4530)
- Loïc de Pontual (ORCID: https://orcid.org/0000-0002-3123-0453)
- Patricia Benhaim
- Simon Escoda (ORCID: https://orcid.org/0000-0001-9328-1945)
- Isabelle Thuret
- Bérangère Koehl
- Jean Gaschignard (ORCID: https://orcid.org/0000-0002-9141-4115)
- Corinne Levy (ORCID: https://orcid.org/0000-0002-5325-5838)
- Cécile Guillaumat
- Inès Fafi (ORCID: https://orcid.org/0009-0001-2516-2175)
- Vincent Gajdos
- Alexandra Gauthier
- Robert Cohen
- Luu‐Ly Pham (ORCID: https://orcid.org/0000-0002-2978-764X)
- Lahoueri Amor‐Chelihi
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Hôpital Necker-Enfants Malades (FR)
- Inserm (FR)
- Université Paris-Est Créteil (FR)
- Université Paris Cité (FR)
- Université Paris-Saclay (FR)
- Assistance Publique Hôpitaux de Marseille (FR)
- Institut d’Hématologie et d’Oncologie Pédiatrique (FR)
- Université Sorbonne Paris Nord (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospices Civils de Lyon (FR)
- Centre Hospitalier Sud Francilien (FR)
- Hôpital Robert-Debré (FR)
- Association Clinique et Thérapeutique Infantile du Val de Marne (FR)
- Centre Hospitalier Saint-Denis (FR)
- Hôpital Jean-Verdier (FR)
- Hôpital Antoine-Béclère (FR)
- Biologie intégrée du globule rouge et de l'Erythropoïèse (FR)
- Hôpital Intercommunal de Créteil (FR)
- Institut Mondor de Recherche Biomédicale (FR)
- Hôpital de la Timone (FR)
- Infection, Anti-microbiens, Modélisation, Evolution (FR)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1097/inf.0000000000004755
- Citations
- 4
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.50