White Cord Syndrome: Myelopathy Caused by an Ossified Posterior Longitudinal Ligament After Posterior Cervical Laminectomy and Fusion

White cord syndrome (WCS) is a rare but serious postoperative complication after spinal decompression surgery. Risk factors such as advanced age, ossification of the posterior longitudinal ligament (OPLL), and major surgery may have predisposed this patient to develop WCS. This report discusses a 72-year-old Hispanic male patient with cervical stenosis due to OPLL who underwent posterior cervical decompression and fusion. After laminectomy and decompression were done, neuromonitoring signals decreased significantly. Despite intraoperative interventions after neuromonitoring signals decreased (e.g., mean arterial pressure augmentation with vasopressors, intravenous steroid therapy), the patient experienced significant quadriparesis following surgery. On postoperative imaging, spinal cord edema and T2 hyperintensities were noted on cervical MRI, consistent with the descriptions of WCS. The patient's postoperative course was marked by significant complications such as respiratory distress, hemodynamic instability, and infection, which ultimately led to his demise. This case highlights the necessity of individual risk factor stratification prior to surgery, careful neuromonitoring, and prompt treatment to manage suspected WCS.

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Journal
Cureus
Published
2025-03-09
DOI
https://doi.org/10.7759/cureus.80295
Citations
1
Primary Topic
Cervical and Thoracic Myelopathy
Type
article
Field-Weighted Citation Impact
2.01
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article

White Cord Syndrome: Myelopathy Caused by an Ossified Posterior Longitudinal Ligament After Posterior Cervical Laminectomy and Fusion

Ashlie Maldonado-Pérez, Samuel Estronza, Emil A Pastrana, J L Campos et al.
1 citations
Cureus
Cervical and Thoracic Myelopathy
2.01
article

White Cord Syndrome: Myelopathy Caused by an Ossified Posterior Longitudinal Ligament After Posterior Cervical Laminectomy and Fusion

Ashlie Maldonado-Pérez, Samuel Estronza, Emil A Pastrana, J L Campos, Gisela Murray
article en
1 citations

Abstract

White cord syndrome (WCS) is a rare but serious postoperative complication after spinal decompression surgery. Risk factors such as advanced age, ossification of the posterior longitudinal ligament (OPLL), and major surgery may have predisposed this patient to develop WCS. This report discusses a 72-year-old Hispanic male patient with cervical stenosis due to OPLL who underwent posterior cervical decompression and fusion. After laminectomy and decompression were done, neuromonitoring signals decreased significantly. Despite intraoperative interventions after neuromonitoring signals decreased (e.g., mean arterial pressure augmentation with vasopressors, intravenous steroid therapy), the patient experienced significant quadriparesis following surgery. On postoperative imaging, spinal cord edema and T2 hyperintensities were noted on cervical MRI, consistent with the descriptions of WCS. The patient's postoperative course was marked by significant complications such as respiratory distress, hemodynamic instability, and infection, which ultimately led to his demise. This case highlights the necessity of individual risk factor stratification prior to surgery, careful neuromonitoring, and prompt treatment to manage suspected WCS.

CureusVol. 17(3)
University of Puerto Rico, Medical Sciences Campus (PR), San Juan Bautista School of Medicine (PR)
Good health and well-being
Openalex Percentile: Top 18%
Cervical and Thoracic Myelopathy
2.01
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White Cord Syndrome: Myelopathy Caused by an Ossified Posterior Longitudinal Ligament After Posterior Cervical Laminectomy and Fusion — Ashlie Maldonado-Pérez, Samuel Estronza, et al. · Cureus (2025) | TGRS Research Map | TGRS