Serum sortilin-derived propeptide concentrations as markers of depression in chronic stroke

These findings suggest serum sortilin-derived propeptide could be a useful biomarker for post-stroke depression. This opens up potential new treatment approaches, including the consideration of the drug spadin, which targets this peptide, for managing post-stroke depression in humans.

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Publication Details

Journal
Journal of the Neurological Sciences
Published
2025-03-08
DOI
https://doi.org/10.1016/j.jns.2025.123459
Citations
2
Primary Topic
Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
1.68
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article

Serum sortilin-derived propeptide concentrations as markers of depression in chronic stroke

Catherine Heurteaux, Marc Borsotto, Anne-Marie Mendyk, Jean Mazella et al.
2 citations
Journal of the Neurological Sciences
Neurological Disorders and Treatments
1.68
article

Serum sortilin-derived propeptide concentrations as markers of depression in chronic stroke

Catherine Heurteaux, Marc Borsotto, Anne-Marie Mendyk, Jean Mazella, Thibaut Dondaine, Régis Bordet, Bertrand Accart, Estelle Mazella
article en
2 citations

Abstract

These findings suggest serum sortilin-derived propeptide could be a useful biomarker for post-stroke depression. This opens up potential new treatment approaches, including the consideration of the drug spadin, which targets this peptide, for managing post-stroke depression in humans.

Journal of the Neurological SciencesVol. 472
Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Côte d'Azur (FR), Université de Lille (FR), Centre Hospitalier Universitaire de Lille (FR), Institut de Pharmacologie Moléculaire et Cellulaire (FR), Lille Neurosciences & Cognition (FR)
Good health and well-being
Openalex Percentile: Top 17%
Neurological Disorders and Treatments
1.68
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Serum sortilin-derived propeptide concentrations as markers of depression in chronic stroke — Catherine Heurteaux, Marc Borsotto, et al. · Journal of the Neurological Sciences (2025) | TGRS Research Map | TGRS