Improvement in long-term survival with mesenchymal stem cell transplantation in systemic sclerosis patients: a propensity score-matched cohort study
MSCT significantly enhances the survival rate of patients with SSc, with outcomes related to the age at diagnosis. MSCT is particularly indicated for patients with comorbid conditions, including PAH, ILD, digital ulcers, and arthritis, as well as those with severe disease presentations associated with the dcSSc subtype.
Authors
- Dapeng Yang (ORCID: https://orcid.org/0000-0001-8687-4486)
- Linyu Geng (ORCID: https://orcid.org/0000-0002-8983-2326)
- Zhikang Wang (ORCID: https://orcid.org/0009-0001-7590-8406)
- Xuebing Feng (ORCID: https://orcid.org/0000-0002-9837-9690)
- Mian Liu (ORCID: https://orcid.org/0000-0002-5406-5067)
- Xuan Cao (ORCID: https://orcid.org/0000-0002-6859-0030)
- Ziyi Jin (ORCID: https://orcid.org/0000-0002-8091-2266)
- Dandan Wang (ORCID: https://orcid.org/0000-0002-9370-0668)
- Lingyun Sun (ORCID: https://orcid.org/0000-0002-8563-2036)
- Jun Liang (ORCID: https://orcid.org/0000-0001-5536-6569)
- Wenyi Yuan (ORCID: https://orcid.org/0000-0003-3315-8229)
- Huayong Zhang (ORCID: https://orcid.org/0000-0003-0125-2755)
- Yirui Shi
Institutions
- Nanjing University of Chinese Medicine (CN)
- Xuzhou Medical College (CN)
- Nanjing Drum Tower Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-03-09
- DOI
- https://doi.org/10.1186/s13287-025-04237-1
- Citations
- 7
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 10.30
Funders
- Innovative Research Group Project of the National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province
- Jiangsu Provincial Key Research and Development Program
- Nanjing Drum Tower Hospital