Opposite causal effects of type 2 diabetes and metformin on Alzheimer's disease
Our study reveals the opposite independent causal effects of T2D and metformin exposure on AD. These findings highlight the importance of assessing AD risk when prescribing metformin to patients with T2D.
Authors
- Ancha Baranova (ORCID: https://orcid.org/0000-0001-6810-5982)
- Hongbao Cao (ORCID: https://orcid.org/0000-0001-6591-9518)
- Fuquan Zhang (ORCID: https://orcid.org/0000-0003-3204-8191)
- Dongming Liu (ORCID: https://orcid.org/0000-0003-1317-1610)
- Chenxin Xu (ORCID: https://orcid.org/0009-0008-2799-8508)
Institutions
- George Mason University (US)
- Renji Hospital (CN)
- Nanjing Brain Hospital (CN)
- Nanjing Drum Tower Hospital (CN)
- Research Centre for Medical Genetics (RU)
Publication Details
- Journal
- The Journal of Prevention of Alzheimer s Disease
- Published
- 2025-03-09
- DOI
- https://doi.org/10.1016/j.tjpad.2025.100129
- Citations
- 2
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 2.33