Gendered social determinants of health and risk of major adverse outcomes in atrial fibrillation

Atrial fibrillation (AF) is associated with adverse outcomes and social determinants of health (SDOH), which are gendered, may predict adverse outcomes in AF. We used a registry of AF patients from 27 European countries. Multivariate logistic regressions were used to investigate the associations between gendered SDOH and the primary outcome, a composite of major adverse cardiovascular events and all-cause mortality. Several SDOH were independent predictors: no higher education (OR:1.17;95 %CI:1.05-1.28), lower health (OR:1.08;95 %CI:1.05-1.11), higher GII (OR:1.12;95 %CI:1.03-1.22 each 0.100), reduced mobility (OR:1.18;95 %CI:1.02-1.38) and reduced self-care (OR:1.35;95 %CI:1.14-1.61). Gendered SDOH are independently associated with adverse events in AF.

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Publication Details

Journal
European Journal of Internal Medicine
Published
2025-03-09
DOI
https://doi.org/10.1016/j.ejim.2025.02.009
Citations
5
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
6.94

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article

Gendered social determinants of health and risk of major adverse outcomes in atrial fibrillation

Colleen M. Norris, Louise Pilote, Jonathan Houle, Marco Proietti et al.
5 citations
European Journal of Internal Medicine
Atrial Fibrillation Management and Outcomes
6.94
article

Gendered social determinants of health and risk of major adverse outcomes in atrial fibrillation

Colleen M. Norris, Louise Pilote, Jonathan Houle, Marco Proietti, Gregory Y.H. Lip, Michał Abrahamowicz, Valeria Raparelli, Clare Atzema, Giuseppe Boriani
article en
5 citations

Abstract

Atrial fibrillation (AF) is associated with adverse outcomes and social determinants of health (SDOH), which are gendered, may predict adverse outcomes in AF. We used a registry of AF patients from 27 European countries. Multivariate logistic regressions were used to investigate the associations between gendered SDOH and the primary outcome, a composite of major adverse cardiovascular events and all-cause mortality. Several SDOH were independent predictors: no higher education (OR:1.17;95 %CI:1.05-1.28), lower health (OR:1.08;95 %CI:1.05-1.11), higher GII (OR:1.12;95 %CI:1.03-1.22 each 0.100), reduced mobility (OR:1.18;95 %CI:1.02-1.38) and reduced self-care (OR:1.35;95 %CI:1.14-1.61). Gendered SDOH are independently associated with adverse events in AF.

European Journal of Internal MedicineVol. 135
University of Modena and Reggio Emilia (IT), University of Liverpool (GB), University of Alberta (CA), University of Ferrara (IT), McGill University Health Centre (CA), Liverpool Heart and Chest Hospital (GB), Istituti Clinici Scientifici Maugeri (IT), Azienda Ospedaliero-Universitaria di Modena (IT), Sunnybrook Hospital (CA), Sunnybrook Research Institute, McGill University (CA)
Canadian Institutes of Health Research
Gender equality
Openalex Percentile: Top 3%
Atrial Fibrillation Management and Outcomes
6.94
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