Gendered social determinants of health and risk of major adverse outcomes in atrial fibrillation
Atrial fibrillation (AF) is associated with adverse outcomes and social determinants of health (SDOH), which are gendered, may predict adverse outcomes in AF. We used a registry of AF patients from 27 European countries. Multivariate logistic regressions were used to investigate the associations between gendered SDOH and the primary outcome, a composite of major adverse cardiovascular events and all-cause mortality. Several SDOH were independent predictors: no higher education (OR:1.17;95 %CI:1.05-1.28), lower health (OR:1.08;95 %CI:1.05-1.11), higher GII (OR:1.12;95 %CI:1.03-1.22 each 0.100), reduced mobility (OR:1.18;95 %CI:1.02-1.38) and reduced self-care (OR:1.35;95 %CI:1.14-1.61). Gendered SDOH are independently associated with adverse events in AF.
Authors
- Colleen M. Norris (ORCID: https://orcid.org/0000-0002-6793-9333)
- Louise Pilote (ORCID: https://orcid.org/0000-0002-6159-0628)
- Jonathan Houle
- Marco Proietti (ORCID: https://orcid.org/0000-0003-1452-2478)
- Gregory Y.H. Lip (ORCID: https://orcid.org/0000-0002-7566-1626)
- Michał Abrahamowicz (ORCID: https://orcid.org/0000-0002-3172-3952)
- Valeria Raparelli (ORCID: https://orcid.org/0000-0002-2100-5682)
- Clare Atzema (ORCID: https://orcid.org/0000-0002-7236-5522)
- Giuseppe Boriani (ORCID: https://orcid.org/0000-0002-9820-4815)
Institutions
- University of Modena and Reggio Emilia (IT)
- University of Liverpool (GB)
- University of Alberta (CA)
- University of Ferrara (IT)
- McGill University Health Centre (CA)
- Liverpool Heart and Chest Hospital (GB)
- Istituti Clinici Scientifici Maugeri (IT)
- Azienda Ospedaliero-Universitaria di Modena (IT)
- Sunnybrook Hospital (CA)
- Sunnybrook Research Institute
- McGill University (CA)
Publication Details
- Journal
- European Journal of Internal Medicine
- Published
- 2025-03-09
- DOI
- https://doi.org/10.1016/j.ejim.2025.02.009
- Citations
- 5
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 6.94
Funders
- Canadian Institutes of Health Research