The action of 7,8-dihydroxyflavone preserves retinal ganglion cell survival and visual function via the TrkB pathway in NMDA-induced retinal excitotoxicity
Different RGC types exhibit variable susceptibilities to NMDA injury, and DHF-mediated activation of TrkB affords neuroprotection.
Authors
- Marcelino Avilés‐Trigueros (ORCID: https://orcid.org/0000-0001-9711-2196)
- Caridad Galindo‐Romero (ORCID: https://orcid.org/0000-0001-9469-9868)
- Pedro de la Villa (ORCID: https://orcid.org/0000-0001-9856-6616)
- José Manuel Bernal-Garro
- Manuel Vidal‐Sanz (ORCID: https://orcid.org/0000-0002-9216-1615)
- Beatriz Vidal‐Villegas (ORCID: https://orcid.org/0000-0001-9352-1400)
- Alejandro Gallego‐Ortega (ORCID: https://orcid.org/0000-0001-6770-7463)
Institutions
- Universidad de Alcalá (ES)
- Instituto Murciano de Investigación Biosanitaria (ES)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1016/j.biopha.2025.117944
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministerio de Ciencia, Innovación y Universidades
- European Commission
- Universidad de Murcia
- European Regional Development Fund