Neuroinflammation causes mitral cell dysfunction and olfactory impairment in a multiple sclerosis model
This study reveals the crucial role of mitral cells and their potassium channel activity in the olfactory bulb during EAE, thereby enhancing our understanding of neuroinflammation-induced neurodegeneration in MS.
Authors
- Manuel Alexander Friese (ORCID: https://orcid.org/0000-0001-6380-2420)
- Christian Lohr (ORCID: https://orcid.org/0000-0001-6518-6422)
- Fabio Morellini (ORCID: https://orcid.org/0000-0002-5185-3850)
- Vanessa Vieira (ORCID: https://orcid.org/0000-0002-0205-9669)
- Marcel S. Woo (ORCID: https://orcid.org/0000-0002-1306-2708)
- Alexandros Hadjilaou (ORCID: https://orcid.org/0000-0002-2443-9611)
- Nina Meurs (ORCID: https://orcid.org/0000-0001-5366-0123)
- Kristina Schulz (ORCID: https://orcid.org/0009-0003-5626-1613)
- Daniela Hirnet (ORCID: https://orcid.org/0009-0004-0566-4604)
- Jana K. Sonner (ORCID: https://orcid.org/0000-0002-4700-272X)
- Charlotte Schubert (ORCID: https://orcid.org/0000-0002-2967-4290)
- Anna-Lena Seemann
- Janine Gierke
Institutions
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Institute of Neuroimmunology of the Slovak Academy of Sciences (SK)
- Bernhard Nocht Institute for Tropical Medicine (DE)
Publication Details
- Journal
- Journal of Neuroinflammation
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1186/s12974-025-03388-5
- Citations
- 4
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.86
Funders
- Deutsche Forschungsgemeinschaft