Association between cardiac autonomic dysfunction, cognitive impairment, and survival in patients with amyotrophic lateral sclerosis
Patients with ALS with cognitive impairment demonstrated reduced cardiac autonomic modulations and altered cognitive autonomic associations. Cognitive impairment was linked to reduced survival, with baseline SDNN ≤ 100 ms identified as a potential marker.
Authors
- Zhenxiang Gong (ORCID: https://orcid.org/0000-0001-6105-0587)
- Jingjing Fan (ORCID: https://orcid.org/0000-0002-1110-5735)
- Jiahui Tang (ORCID: https://orcid.org/0009-0001-2191-5053)
- Min Zhang (ORCID: https://orcid.org/0000-0001-8083-5603)
- Mao Liu (ORCID: https://orcid.org/0000-0002-5932-2712)
- Zehui Li (ORCID: https://orcid.org/0000-0003-2354-5356)
- Yuan Yang (ORCID: https://orcid.org/0000-0002-1259-5334)
Institutions
- Shanxi Medical University (CN)
- SUNY Downstate Health Sciences University (US)
- First Affiliated Hospital of Xiamen University (CN)
- The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture (CN)
- Shanxi Academy of Medical Sciences (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Clinical Autonomic Research
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1007/s10286-025-01112-0
- Citations
- 2
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- National Natural Science Foundation of China
- Tongji University