Plasmidome analyses of Klebsiella pneumoniae co-producing blaKPC-2 and blaNDM-1 in Southern Brazil: characterisation of mobile genetic elements

Plasmid and transposon changes during different periods could be related to higher dissemination of bla<sub>NDM-1</sub>, and the large number of resistance genes present in the IS26-flanked transposon may have increased co-selection of this plasmid through the wide use of antimicrobials during the pandemic.

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Publication Details

Journal
Journal of Global Antimicrobial Resistance
Published
2025-03-08
DOI
https://doi.org/10.1016/j.jgar.2025.02.020
Citations
3
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
1.77
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article

Plasmidome analyses of Klebsiella pneumoniae co-producing blaKPC-2 and blaNDM-1 in Southern Brazil: characterisation of mobile genetic elements

C Wilhem, Daniella Cristina Rodrigues Pereira, Patricia Orlandi Barth, Melise Chaves Silveira et al.
3 citations
Journal of Global Antimicrobial Resistance
Antibiotic Resistance in Bacteria
1.77
article

Plasmidome analyses of Klebsiella pneumoniae co-producing blaKPC-2 and blaNDM-1 in Southern Brazil: characterisation of mobile genetic elements

C Wilhem, Daniella Cristina Rodrigues Pereira, Patricia Orlandi Barth, Melise Chaves Silveira, Afonso Luís Barth, Ana Paula D’Alincourt Carvalho-Assef, Fabiana Caroline Zempulski Volpato, Ricardo Romão Guerra, Cláudio Marcos Rocha-de-Souza, Alessandro F. Martins, Richard Martins Carrassai, Mayana Berdichevski
article en
3 citations

Abstract

Plasmid and transposon changes during different periods could be related to higher dissemination of bla<sub>NDM-1</sub>, and the large number of resistance genes present in the IS26-flanked transposon may have increased co-selection of this plasmid through the wide use of antimicrobials during the pandemic.

Journal of Global Antimicrobial ResistanceVol. 42
Universidade Federal do Rio Grande do Sul (BR), Hospital de Clínicas de Porto Alegre (BR), Fundação Oswaldo Cruz (BR)
Openalex Percentile: Top 17%
Antibiotic Resistance in Bacteria
1.77
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