Association of long-term insulin variability before the onset of diabetes with cardiovascular outcomes in later life: Findings from the coronary artery risk development in young adults (CARDIA) study
High long-term insulin variability in young adulthood before the onset of diabetes was associated with an increased risk of CVD and all-cause mortality in later life, independent of average FG, HOMA-IR and other established cardiovascular risk factors. Long-term insulin variability was associated with the degree but not the presence of CAC.
Authors
- Chunlan Huang (ORCID: https://orcid.org/0000-0001-7269-2120)
- F. Huang (ORCID: https://orcid.org/0000-0002-6014-5928)
- Weijing Feng (ORCID: https://orcid.org/0000-0001-6997-9606)
- Wanbing He (ORCID: https://orcid.org/0000-0001-5892-9822)
- Peibiao Mai (ORCID: https://orcid.org/0000-0001-5363-3504)
- Huanji Zhang (ORCID: https://orcid.org/0000-0003-2920-2928)
- Kun Zhang (ORCID: https://orcid.org/0000-0002-8268-1051)
- Yang Liu (ORCID: https://orcid.org/0000-0002-7945-6611)
- Junping Li
- Shuwan Xu
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Peking University Third Hospital (CN)
- Guangdong Provincial People's Hospital (CN)
- Fu Wai Hospital (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
- Southern Medical University (CN)
- University of South China (CN)
Publication Details
- Journal
- American Journal of Preventive Cardiology
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1016/j.ajpc.2025.100952
- Citations
- 1
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 1.39