Naoqing formula alleviates cerebral ischemia/reperfusion injury induced inflammatory injury by regulating Csf3 mediated JAK/STAT pathway and macrophage polarization
This study confirmed that NQ prevented CIRI induced inflammatory injury by inhibiting Csf3-mediated activation of the JAK/STAT pathway and modulating Csf3-mediated macrophage polarization. This study provided a new perspective on the use of NQ in the treatment of IS.
Authors
- Xin Xie (ORCID: https://orcid.org/0000-0002-6784-4860)
- Zhuqing Rao (ORCID: https://orcid.org/0000-0001-8551-0074)
- Yiming Bi (ORCID: https://orcid.org/0000-0002-4368-3783)
- Chengyin Wang (ORCID: https://orcid.org/0000-0001-6831-6675)
- Yingxin Liu (ORCID: https://orcid.org/0000-0002-6859-6993)
- Ting Zeng (ORCID: https://orcid.org/0000-0001-6041-4211)
- Lingling Qiu (ORCID: https://orcid.org/0000-0002-4228-6540)
- Xuchu Weng
- Y Ye
- Qing Liu (ORCID: https://orcid.org/0009-0008-9320-450X)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Guangzhou University (CN)
- Foshan Hospital of TCM (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1016/j.phymed.2025.156626
- Citations
- 6
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.05