CFTR modulators and pregnancy outcomes: Early findings from a nationwide cohort study
The study provides early reassurance about the safety of CFTR modulators during pregnancy, particularly in terms of teratogenicity and adverse pregnancy outcomes. While findings suggest potential benefits, such as halved rate of SGA, further research is required to confirm these outcomes and investigate long-term effects on the development of children prenatally exposed to CFTR modulators.
Authors
- Laurent Chouchana (ORCID: https://orcid.org/0000-0002-9626-3571)
- Clémence Martin (ORCID: https://orcid.org/0000-0003-4385-5888)
- Pierre‐Régis Burgel (ORCID: https://orcid.org/0000-0003-0903-9828)
- Mathis Collier (ORCID: https://orcid.org/0009-0000-2398-0396)
- Jean‐Marc Tréluyer (ORCID: https://orcid.org/0000-0002-2045-4742)
Institutions
- Délégation Paris 5 (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- Sorbonne Paris Cité (FR)
- Hôpital Cochin (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Institut Cochin (FR)
Publication Details
- Journal
- Journal of Cystic Fibrosis
- Published
- 2025-03-09
- DOI
- https://doi.org/10.1016/j.jcf.2025.03.002
- Citations
- 13
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 19.74