PET imaging of functional 5-HT1A receptors with [18F]F13640: From PET kinetics modeling to static Standardized Uptake Values Ratio
This study confirms the feasibility of static acquisitions to facilitate clinical use of the [<sup>18</sup>F]F13640 radiopharmaceutical to image functional 5-HT<sub>1A</sub> receptors. This involves off-camera injection, 10 to 20 mins static acquisition duration, and quantification using SUVR, while improving patient comfort.
Authors
- Jérôme Redouté (ORCID: https://orcid.org/0000-0002-3741-1546)
- Inès Mérida (ORCID: https://orcid.org/0000-0003-1436-4684)
- Luc Zimmer (ORCID: https://orcid.org/0000-0002-2805-7098)
- Nicolas Costes (ORCID: https://orcid.org/0000-0002-2954-9262)
- Sophie Lancelot (ORCID: https://orcid.org/0000-0002-3637-8035)
- Pierre Courault (ORCID: https://orcid.org/0000-0002-1654-4753)
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Centre de Recherche en Neurosciences de Lyon (FR)
- Hospices Civils de Lyon (FR)
- Centre d'Exploration et de Recherche Médicale par Emission de Positons (FR)
Publication Details
- Journal
- NeuroImage
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1016/j.neuroimage.2025.121110
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00