Antibodies Are Predictive for Diagnosis of Celiac Disease in Pediatric Type 1 Diabetes
Our results suggest an indication for biopsy for CD confirmation at a TGA-IgA cutoff around 6.1 × upper limit of normal. Including IgG antibodies against deamidated gliadin peptides can potentially increase precision. TGA-IgA determination at T1D diagnosis may help to identify individuals at risk of CD early on.
Authors
- Arnaud Künzi (ORCID: https://orcid.org/0000-0003-3115-9156)
- Claudia Boettcher (ORCID: https://orcid.org/0000-0001-5494-2616)
- Christiane Sokollik (ORCID: https://orcid.org/0000-0002-5992-8247)
- Marie‐Anne Burckhardt (ORCID: https://orcid.org/0000-0002-6274-5900)
- Barblin Remund
- I Mureşan (ORCID: https://orcid.org/0000-0003-1483-7752)
- Norbert Müller
- Zamir-Zoran Borojevic
Institutions
- University of Bern (CH)
- Bern University of Applied Sciences (CH)
- University Hospital of Bern (CH)
- University Children’s Hospital Basel (CH)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1210/clinem/dgaf146
- Citations
- 2
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 3.62