Rare severe hereditary maxillary hypoplasia associated with multiple agenesis of the permanent teeth in 2 brothers: A report of 2 cases

Severe maxillary hypoplasia is a rare craniofacial deformity that significantly impacts facial esthetics and function. This condition is even more challenging when associated with multiple agenesis of permanent teeth. We present a case report of 2 brothers from a consanguineous family (degree 2), both diagnosed with hereditary maxillary hypoplasia accompanied by multiple missing permanent teeth. Clinical and radiographic evaluations were conducted to investigate the etiology and propose a multidisciplinary approach to management. This report aims to highlight the clinical features, diagnostic approach, and treatment considerations for this rare condition.