Unveiling the enigma: A rare case of eosinophilic granuloma

Eosinophilic granuloma is a benign and mildest subtype of Langerhans cell histiocytosis. It has a predilection for males with age less than ten years. It presents with localized swelling in the skull, long bones, or rarely mandible. We report the case of a 17-year-old male who presented with swelling in the frontal area of his head which was tender. On radiographic imaging, ovoid lytic lesions with beveled edges were noticed. On computed tomography multiple osteolytic lesions in the bilateral frontal region focally eroding both the inner and outer cranial tables were seen. Upon confirmation of the diagnosis patient was taken up for surgical intervention. The calvarial deformity was closed by a titanium mesh.

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Publication Details

Journal
Radiology Case Reports
Published
2025-03-08
DOI
https://doi.org/10.1016/j.radcr.2025.02.026
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Unveiling the enigma: A rare case of eosinophilic granuloma

Shivali Kashikar, Pratapsingh Parihar, Utkarsh Pradeep, Paschyanti R Kasat et al.
Radiology Case Reports
Histiocytic Disorders and Treatments
article

Unveiling the enigma: A rare case of eosinophilic granuloma

Shivali Kashikar, Pratapsingh Parihar, Utkarsh Pradeep, Paschyanti R Kasat, Pratiksha Sachani
article en

Abstract

Eosinophilic granuloma is a benign and mildest subtype of Langerhans cell histiocytosis. It has a predilection for males with age less than ten years. It presents with localized swelling in the skull, long bones, or rarely mandible. We report the case of a 17-year-old male who presented with swelling in the frontal area of his head which was tender. On radiographic imaging, ovoid lytic lesions with beveled edges were noticed. On computed tomography multiple osteolytic lesions in the bilateral frontal region focally eroding both the inner and outer cranial tables were seen. Upon confirmation of the diagnosis patient was taken up for surgical intervention. The calvarial deformity was closed by a titanium mesh.

Radiology Case ReportsVol. 20(5)
Jawaharlal Nehru Medical College (IN), Datta Meghe Institute of Higher Education and Research (IN)
Openalex Percentile: Top 94%
Histiocytic Disorders and Treatments
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