Real-World Effectiveness and Safety of Upadacitinib in Crohn’s Disease: A Multicenter Study
UPA was effective at inducing clinical and endoscopic remission in a real-world group of patients with CD, even with prior exposure to multiple prior advanced therapies. No new safety concerns were identified.
Authors
- Nikhil Reddy
- Amanda M. Johnson (ORCID: https://orcid.org/0000-0003-2838-0538)
- Abdul Wali Khan (ORCID: https://orcid.org/0000-0002-5450-930X)
- Jeremy A. Klein (ORCID: https://orcid.org/0000-0002-1996-3451)
- Marc Fenster
- Anthony Xu (ORCID: https://orcid.org/0000-0001-9330-2582)
- Ryan C. Ungaro (ORCID: https://orcid.org/0000-0001-8687-3758)
- Andrés Yarur (ORCID: https://orcid.org/0000-0003-2293-5555)
- Shrinivas Bishu (ORCID: https://orcid.org/0000-0003-4823-5805)
- Jalpa Devi (ORCID: https://orcid.org/0000-0001-8710-2381)
- Fnu Jaiprada
- Joel Pekow (ORCID: https://orcid.org/0000-0002-4790-8994)
- Navreet Chowla (ORCID: https://orcid.org/0009-0009-8882-5579)
- Caroline Benson
- Anish Patel (ORCID: https://orcid.org/0000-0002-1880-7991)
- Katherine Huang (ORCID: https://orcid.org/0000-0002-5013-4790)
- Molly Stone
- Julia B. Huecker
- Bryan Christopher Luu
Institutions
- Cedars-Sinai Medical Center (US)
- Brooke Army Medical Center (US)
- Mayo Clinic (US)
- Montefiore Medical Center (US)
- Baylor College of Medicine (US)
- Washington University in St. Louis (US)
- University of Michigan (US)
- Wilford Hall Ambulatory Surgical Center (US)
- University of Chicago (US)
- Mayo Clinic in Arizona (US)
- Institute for Medical Informatics and Biostatistics (CH)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Clinical Gastroenterology and Hepatology
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1016/j.cgh.2025.01.012
- Citations
- 8
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 14.54
Funders
- Crohn's and Colitis Foundation of America
- American College of Gastroenterology