Randomized double blind placebo controlled multicentric clinical trial of Ayush M-3 in the management of migraine- A study protocol
The primary outcomes measures for the study will be changes in the character of disease in terms of frequency, intensity of headache as per VAS (0-10) and duration of episode of headache. Secondary outcome measure will be changes in MIDAS, MSQ2.1, changes in associated symptoms of migraine, change in the use of analgesics/symptom alleviating medication & Change in the required dose/withdrawal of Anti-hypertensive drugs if any. Assessment will be conducted on an interval of 28 days till 16 weeks and an intervention free follow up at the end of week 20.
Authors
- Bharti Bharti (ORCID: https://orcid.org/0000-0001-9626-9212)
- K G Sudha Kumari (ORCID: https://orcid.org/0000-0002-1561-9995)
- Rakesh Kumar Rana (ORCID: https://orcid.org/0000-0002-3115-0701)
- B C S Rao (ORCID: https://orcid.org/0000-0001-5408-3225)
- Renu Makhija
- Richa Singhal
- Sunita Mata (ORCID: https://orcid.org/0000-0002-4878-7602)
- N Srikanth
- Kartar Singh Dhiman (ORCID: https://orcid.org/0000-0003-4991-907X)
- Shweta Chaudhary (ORCID: https://orcid.org/0000-0002-2514-2975)
- Shruti Khanduri (ORCID: https://orcid.org/0000-0001-6310-6505)
- Rabinarayan Acharya (ORCID: https://orcid.org/0000-0003-4413-1937)
- Rajesh Kumar (ORCID: https://orcid.org/0000-0002-8743-7541)
- Kuljeet Singh Anand (ORCID: https://orcid.org/0009-0001-8993-3944)
- Bidhan Mahajan
- Shweta Mata
Institutions
- Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital (IN)
- Central Council for Research in Ayurvedic Science (IN)
- Ministry of AYUSH (IN)
- CM Hospital (KR)
- Engineers India (India) (IN)
- National Institute of Mental Health and Neurosciences (IN)
- National Institute of Malaria Research (IN)
Publication Details
- Journal
- Journal of Ayurveda and Integrative Medicine
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.jaim.2024.101054
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of AYUSH, Government of India