Net albumin leakage in patients in the ICU with suspected sepsis. A prospective analysis using mass balance calculations
This study demonstrated a net positive albumin leakage of 8 ± 10 g over 24 h in ICU patients with suspected sepsis, with a weak early correlation to pro-inflammatory cytokines but no significant link to fluid balance or glycocalyx shedding. Notably, albumin infusions were associated with increased net leakage.
Authors
- Åke Norberg
- Jan Wernerman (ORCID: https://orcid.org/0000-0003-1343-7773)
- Nicolas Tardif (ORCID: https://orcid.org/0000-0002-5022-1093)
- Olav Rooyackers (ORCID: https://orcid.org/0000-0002-3391-5448)
- Dag Seldén
Institutions
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Critical Care
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1186/s13054-025-05323-9
- Citations
- 5
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.77
Funders
- Karolinska Institutet
- Stockholm läns landsting