Lysozyme modulates inflammatory responses to exacerbate the severity of rheumatoid arthritis
LYZ is highly expressed in the plasma and synovial fluid macrophages of early RA patients and exacerbates RA progression by modulating inflammation-related pathways, demonstrating potential as a biomarker for early RA diagnosis or a therapeutic target.
Authors
- Yihong Liu (ORCID: https://orcid.org/0000-0001-8324-7460)
- Jinxiang Han (ORCID: https://orcid.org/0000-0002-2507-9611)
- Wenyue Zhang (ORCID: https://orcid.org/0000-0001-8181-8282)
- Luxu Yin
- Enshui Zhang
- Cheng Yang (ORCID: https://orcid.org/0000-0002-5608-3680)
- Yan Zhao (ORCID: https://orcid.org/0000-0002-4529-1206)
- Hao Xu (ORCID: https://orcid.org/0000-0002-8311-506X)
- Liang Zou
Institutions
- Shandong First Medical University (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1016/j.intimp.2025.114427
- Citations
- 7
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 11.68