Vitamin D Deficiency During Pregnancy

Even though vitamin D deficiency during pregnancy has become an area of ​​increased research interest, the function of vitamin D during pregnancy for both the mother and fetus remains largely undefined. Our review aims to examine the role of vitamin D deficiency in the course and outcome of pregnancy. Results: Many lines of evidence have shown an association between vitamin D deficiency and maternal and fetal complications during pregnancy. In some recent publications, changes in vitamin D and vitamin D binding protein (VDBP) levels in cervicovaginal fluid have been discussed as biomarkers of vaginal inflammation and predictors of the risk of preterm birth, several weeks before delivery. There are contradictory reports regarding the role of vitamin D and the risk of preterm birth. Preterm amniotic fluid spillage and preterm birth are associated with vitamin D deficiency and the inflammatory response. Vitamin D deficiency is a risk factor for preeclampsia and increases the likelihood of cesarean section. Conclusion Vitamin D deficiency during pregnancy is associated with complications of pregnancy and childbirth; Different opinions regarding the impact of vitamin D deficiency during pregnancy, require further research considering population characteristics.