Overexpression of CX3CL1-CX3CR1 Signaling in the Stria Vascularis rather than the Basilar Membrane May Be the Trigger for Inflammaging in the Cochlea

The overexpression of CX3CL1 in the basal cells of the SV with aging may be a trigger point for activating the local inflammatory microenvironment in age-related hearing loss, but it still requires further in vivo intervention experiments for validation.

Authors

Mengqi Zhao (ORCID: https://orcid.org/0000-0002-1230-2116)
Qiyang Sun (ORCID: https://orcid.org/0000-0001-5978-0310)
Fanqin Wei
Weiping Wen (ORCID: https://orcid.org/0000-0001-9354-344X)
Xiaomei Sun (ORCID: https://orcid.org/0000-0002-6650-2260)

Institutions

Sun Yat-sen University (CN)
Sixth Affiliated Hospital of Sun Yat-sen University (CN)
The First Affiliated Hospital, Sun Yat-sen University (CN)

Publication Details

Journal: ORL
Published: 2025-03-08
DOI: https://doi.org/10.1159/000545134
Citations: 1
Primary Topic: Hearing, Cochlea, Tinnitus, Genetics
Type: article
Field-Weighted Citation Impact: 1.46

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article

Overexpression of CX3CL1-CX3CR1 Signaling in the Stria Vascularis rather than the Basilar Membrane May Be the Trigger for Inflammaging in the Cochlea

Mengqi Zhao, Qiyang Sun, Fanqin Wei, Weiping Wen et al.

Mar 8, 2025

1 citations

ORL

Hearing, Cochlea, Tinnitus, Genetics

1.46

article

Overexpression of CX3CL1-CX3CR1 Signaling in the Stria Vascularis rather than the Basilar Membrane May Be the Trigger for Inflammaging in the Cochlea

Mengqi Zhao, Qiyang Sun, Fanqin Wei, Weiping Wen, Xiaomei Sun

March 8, 2025article en

1 citations

Abstract

The overexpression of CX3CL1 in the basal cells of the SV with aging may be a trigger point for activating the local inflammatory microenvironment in age-related hearing loss, but it still requires further in vivo intervention experiments for validation.

ORLVol. 87(1)

Sun Yat-sen University (CN), Sixth Affiliated Hospital of Sun Yat-sen University (CN), The First Affiliated Hospital, Sun Yat-sen University (CN)

Openalex Percentile: Top 24%

Hearing, Cochlea, Tinnitus, Genetics

1.46

DOI Source OpenAlex

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Overexpression of CX3CL1-CX3CR1 Signaling in the Stria Vascularis rather than the Basilar Membrane May Be the Trigger for Inflammaging in the Cochlea — Mengqi Zhao, Qiyang Sun, et al. · ORL (2025) | TGRS Research Map | TGRS