Post-transcriptional regulation in early cell fate commitment of germ layers
Substantial post-transcriptional modulation was found during germ layer commitment, emphasizing the translatome potency in capturing nuanced gene expression regulation. These findings highlight the post-transcriptional regulation's critical role in early embryonic development, offering new insights into the molecular mechanisms of cell differentiation.
Authors
- Annanda Lyra Ribeiro (ORCID: https://orcid.org/0000-0001-6661-9525)
- Lucía Spangenberg (ORCID: https://orcid.org/0000-0001-5124-9250)
- Bruno Dallagiovanna (ORCID: https://orcid.org/0000-0001-6992-7048)
- Cíntia Delai da Silva Horinouchi (ORCID: https://orcid.org/0000-0003-1040-2786)
- Isabela Tiemy Pereira (ORCID: https://orcid.org/0000-0001-8951-9965)
- Aruana Hansel-Frose (ORCID: https://orcid.org/0000-0002-1133-7464)
- Rubens Gomes-Júnior (ORCID: https://orcid.org/0000-0002-7714-5094)
Institutions
- Universidad de la República de Uruguay (UY)
- Fundação Carlos Chagas (BR)
- Institut Pasteur de Montevideo (UY)
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1186/s12864-025-11400-8
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Fundação Oswaldo Cruz