Reduced reproductive potential in young healthy women with hereditary breast and/or ovarian cancer syndrome
A consistent trend for reduced reproductive potential in young, healthy women with HBOC syndrome is observed, particularly in BRCA1 P/LPV carriers. These findings need to be confirmed by larger studies including also women carrying P/LPV in other HBOC syndrome-related genes.
Authors
- Fedro A. Peccatori (ORCID: https://orcid.org/0000-0001-8227-8740)
- Angela Toss (ORCID: https://orcid.org/0000-0002-1854-6701)
- Antonio La Marca (ORCID: https://orcid.org/0000-0001-7921-9547)
- Roberto D’Amico (ORCID: https://orcid.org/0000-0002-3211-6687)
- Massimo Dominici (ORCID: https://orcid.org/0000-0002-4007-1503)
- Renato Bruni (ORCID: https://orcid.org/0000-0002-5992-8722)
- Elena Tenedini (ORCID: https://orcid.org/0000-0003-0285-765X)
- Marta Venturelli (ORCID: https://orcid.org/0000-0003-0658-8004)
- Claudia Piombino (ORCID: https://orcid.org/0000-0002-7224-4536)
- Elena Barbieri (ORCID: https://orcid.org/0000-0002-3480-7983)
- Laura Cortesi
- Matteo Lambertini (ORCID: https://orcid.org/0000-0003-1797-5296)
- Giovanna Sighinolfi
- Chiara Melotti
- Giovanni Grandi
- Riccardo Costantini Cuoghi
Institutions
- University of Modena and Reggio Emilia (IT)
- Azienda Ospedaliero-Universitaria di Modena (IT)
- Ospedale Policlinico San Martino (IT)
- European Institute of Oncology (IT)
- University of Genoa (IT)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1038/s43856-025-00788-9
- Citations
- 2
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.63