The Role of <scp>IgE</scp> in Crohn's Disease by Impairing the Capacity of Plasmacytoid Dendritic Cells to Generate <scp>FOXP3</scp> <sup>+</sup> Tregs
IgE might play an unprecedented role in CD by impairing the capacity of pDCs to generate Tregs, which could represent a novel mechanism contributing to CD to be exploited for alternative therapeutic interventions.
Authors
- Cristina Benito‐Villalvilla (ORCID: https://orcid.org/0000-0002-5544-0199)
- Carlos Taxonera (ORCID: https://orcid.org/0000-0001-9166-7350)
- Leticia Martín‐Cruz (ORCID: https://orcid.org/0000-0002-2546-1183)
- Óscar Palomares (ORCID: https://orcid.org/0000-0003-4516-0369)
- Andrés de la Rocha‐Muñoz (ORCID: https://orcid.org/0000-0003-0168-7943)
- Xavier Jaumont (ORCID: https://orcid.org/0000-0002-4197-1634)
- David Olivares (ORCID: https://orcid.org/0000-0003-3506-7355)
- Sofía Sirvent (ORCID: https://orcid.org/0000-0003-0050-8579)
- Alba Angelina (ORCID: https://orcid.org/0000-0001-5282-9767)
- Paolo Tassinari (ORCID: https://orcid.org/0000-0003-0205-1795)
- Miguel A. García‐Brenes
- Javier Cuesta
Institutions
- Universidad Complutense de Madrid (ES)
- Novartis (Switzerland) (CH)
- Instituto de Salud Carlos III (ES)
- Hospital Clínico San Carlos (ES)
- Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (ES)
- Hospital Universitario Fundación Jiménez Díaz (ES)
- Universidad Autónoma de Madrid (ES)
Publication Details
- Journal
- Allergy
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1111/all.16517
- Citations
- 4
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 3.19
Funders
- Novartis Pharma