Valacyclovir for the prevention of cytomegalovirus infection after kidney transplantation
Valacyclovir prophylaxis after KT significantly reduced CMV infection and rejection. We suggest that valacyclovir could be considered as an alternative strategy for CMV prophylaxis after KT. However, our study has limitations, including its retrospective design, variability in valacyclovir dosing and CMV monitoring, and unassessed confounding factors. Further prospective studies with standardized protocols and larger cohorts are needed to validate our findings.
Authors
- Woo Yeong Park (ORCID: https://orcid.org/0000-0003-2662-2898)
- Juhan Lee (ORCID: https://orcid.org/0000-0003-4910-2596)
- Jin Seok Jeon (ORCID: https://orcid.org/0000-0003-2421-2289)
- Jong Cheol Jeong (ORCID: https://orcid.org/0000-0003-0301-7644)
- Min Jung Ko (ORCID: https://orcid.org/0000-0003-3599-7173)
- Cheol Woong Jung (ORCID: https://orcid.org/0000-0002-0776-8202)
- Jin Sug Kim (ORCID: https://orcid.org/0000-0001-7361-8715)
- Kyung Hwan Jeong (ORCID: https://orcid.org/0000-0003-1492-8021)
- Deok Gie Kim (ORCID: https://orcid.org/0000-0001-9653-926X)
- Na Rae Lee (ORCID: https://orcid.org/0000-0001-6155-9906)
- Hye Eun Yoon (ORCID: https://orcid.org/0000-0002-6347-7282)
- Byung Ha Chung (ORCID: https://orcid.org/0000-0003-0048-5717)
- Jang‐Hee Cho (ORCID: https://orcid.org/0000-0002-7031-5214)
- Soo Jin Na Choi (ORCID: https://orcid.org/0000-0002-0179-731X)
- Jaeseok Yang (ORCID: https://orcid.org/0000-0002-5378-7797)
- Kyun‐Ik Park
- Myoung Soo Kim (ORCID: https://orcid.org/0000-0002-8975-8381)
- Jae Berm Park (ORCID: https://orcid.org/0000-0001-9117-2278)
- Yu Ho Lee (ORCID: https://orcid.org/0000-0001-5231-0551)
- Tae Hyun Ban (ORCID: https://orcid.org/0000-0002-2884-4948)
- Sang Ho Lee (ORCID: https://orcid.org/0000-0002-4634-4904)
- Hyo Jin Kim (ORCID: https://orcid.org/0000-0001-9289-9073)
- Yeong Hoon Kim (ORCID: https://orcid.org/0000-0002-6849-9368)
- Jieun Oh (ORCID: https://orcid.org/0000-0003-3352-9608)
- Hyeon Seok Hwang (ORCID: https://orcid.org/0000-0002-1163-0062)
- Ho Sik Shin
Institutions
- Chonnam National University (KR)
- Hallym University (KR)
- Yonsei University (KR)
- Korea University (KR)
- Severance Hospital (KR)
- Soonchunhyang University Hospital Seoul (KR)
- Kyungpook National University Hospital (KR)
- Kosin University Gospel Hospital (KR)
- Samsung Medical Center (KR)
- Seoul National University Bundang Hospital (KR)
- The Catholic University of Korea Incheon St. Mary's Hospital (KR)
- Wonju Severance Christian Hospital (KR)
- Inje University Busan Paik Hospital (KR)
- Kyung Hee University Medical Center (KR)
- Pusan National University Hospital (KR)
- CHA University Bundang Medical Center (KR)
- National Evidenc- based healthcare Collaborating Agency (KR)
- Kangdong Sacred Heart Hospital (KR)
- CHA University (KR)
- Kyung Hee University Hospital at Gangdong (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Keimyung University (KR)
- Sungkyunkwan University (KR)
- Catholic University of Korea (KR)
- Kosin University (KR)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1186/s12879-025-10671-6
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- National Evidence-based Healthcare Collaborating Agency