Genetic association study between rs2234253 (p.T96K) variant of TREM2 and Alzheimer’s disease in a Tunisian population
Our findings suggest that the TREM2 rs2234253 (p.T96K) variant is a significant genetic risk factor for late-onset AD (LOAD) in the Tunisian population. Further studies with larger cohorts are needed to validate these findings and explore potential gene-gene interactions contributing to AD risk.
Authors
- Saloua Fray (ORCID: https://orcid.org/0000-0002-0848-798X)
- Ghada Baraket (ORCID: https://orcid.org/0000-0003-0886-3268)
- Nadia Ali (ORCID: https://orcid.org/0009-0009-2701-8378)
- Samia Ben Sassi (ORCID: https://orcid.org/0000-0002-1002-5979)
- Afef Achouri-Rassas (ORCID: https://orcid.org/0000-0003-0414-4063)
- Zakaria Abdi Said
Institutions
- Hôpital Charles-Nicolle (TN)
- National Institute of Neurology Mongi-Ben Hamida (TN)
- Tunis El Manar University (TN)
Publication Details
- Journal
- Neurological Research
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1080/01616412.2025.2472841
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.84