IL‐13‐Induced Periostin Expression is Increased in Eosinophilic Chronic Rhinosinusitis
NP tissues from ECRS patients exhibit increased type 2 inflammatory cytokines and periostin. Nasal epithelial cells, particularly basal cells, are an important source of periostin. Exposure to IL-13 is important for periostin production from nasal epithelial cells.
Authors
- Satoshi Nunomura (ORCID: https://orcid.org/0000-0002-9315-4185)
- Eiko Hirabayashi
- Kenji Izuhara
- Mio Takeuchi (ORCID: https://orcid.org/0000-0003-2183-7371)
- Kojiro Hirano (ORCID: https://orcid.org/0000-0002-4466-7953)
- Toshikazu Shimane (ORCID: https://orcid.org/0000-0002-0816-0223)
- Bruce K. Rubin (ORCID: https://orcid.org/0000-0003-0876-4016)
- Isao Suzaki (ORCID: https://orcid.org/0000-0002-9078-1001)
- Yuna Teguchi
Institutions
- SHOWA Medical University (JP)
- Virginia Commonwealth University (US)
- Saga Medical School Hospital (JP)
Publication Details
- Journal
- International Forum of Allergy & Rhinology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1002/alr.23559
- Citations
- 4
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.66
Funders
- Ministry of Education, Culture, Sports, Science and Technology