Evolution of the Florida Pediatric Bone Marrow Transplant and Cell Therapy Consortium (<scp>FPBCC</scp>): A Statewide Initiative Toward Improving Transplant Outcomes
There was a substantial improvement in the 1-year survival of allogeneic transplant recipients treated in FPBCC centers, achieved after the initiation of consortium activities. Within a 3-year period, consortium centers, which had a lower starting point, reached 1-year survival comparable to that of other small and large centers. A significant improvement in survival, although a lesser percentage of change, was seen in other programs of similar size across the country, but not in larger programs. We consider that the magnitude of improvement in survival (12% points or 4% per year), which was not seen among other programs, attests to the effectiveness of consortium activities. A blueprint for improvement in outcomes established by the FPBCC can be shared with other programs around the world that strive to improve posttransplant survival.
Authors
- Warren Alperstein (ORCID: https://orcid.org/0000-0002-1802-5025)
- Deepak Chellapandian (ORCID: https://orcid.org/0000-0003-3518-9790)
- David Crawford (ORCID: https://orcid.org/0000-0002-2467-7556)
- Reema Kashif (ORCID: https://orcid.org/0009-0001-4570-9799)
- Jordan Milner (ORCID: https://orcid.org/0000-0001-5768-7745)
- Mansi Dalal
- Edward Ziga
- John A. Ligon (ORCID: https://orcid.org/0000-0001-5513-1233)
- Michael Joyce (ORCID: https://orcid.org/0009-0000-1253-1472)
- Paul Castillo
- Jorge Galvez‐Silva
- Natalie Booth (ORCID: https://orcid.org/0000-0002-3569-0617)
- Minelys M. Alicea Marrero (ORCID: https://orcid.org/0000-0001-8261-5110)
- Biljana Horn (ORCID: https://orcid.org/0000-0002-1030-5946)
- Jessica Peters (ORCID: https://orcid.org/0000-0002-7195-1482)
- Jin‐Ju Lee
Institutions
- University of Miami (US)
- University of Florida (US)
- Miami Children's Hospital (US)
- Wolfson Children's Hospital (US)
Publication Details
- Journal
- Pediatric Transplantation
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1111/petr.70059
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00