Elucidating the Linkage Between Obesity‐Related Body Fat Indicators and Atrial Fibrillation: Supported by Evidence From Mendelian Randomization and Mediation Analyses
The study reveals that individuals with a higher body fat percentage tend to exhibit a heightened genetic predisposition for susceptibility to AF. Meanwhile, hypertension and sleep apnea syndrome have been identified as key mediators contributing to the pathogenesis of AF.
Authors
- Xiaoming Xie (ORCID: https://orcid.org/0000-0003-0687-4238)
- Wenlin Liu (ORCID: https://orcid.org/0000-0001-7613-5217)
- Jun‐Xian Wang (ORCID: https://orcid.org/0000-0003-3339-2285)
- Shengzhi Zhou
Institutions
- Guangdong Medical College (CN)
- Affiliated Hospital of Guangdong Medical College Hospital (CN)
Publication Details
- Journal
- Clinical Cardiology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/clc.70103
- Citations
- 4
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 7.27