Exploring the Association Between Human Blood Metabolites and Autism Spectrum Disorder Risk: A Bidirectional Mendelian Randomization Study

Our findings indicate that the dodecenedioate, methionine sulfone, cysteine to alanine ratio and proline to glutamate ratio have an impact on ASD. These results enhance our understanding of the metabolic pathways involved in ASD and could lead to new avenues for intervention and prevention. Further research is needed to explore the mechanisms underlying these associations and confirm these findings in different populations.

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Publication Details

Journal
Health Science Reports
Published
2025-03-01
DOI
https://doi.org/10.1002/hsr2.70528
Primary Topic
Autism Spectrum Disorder Research
Type
article
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article

Exploring the Association Between Human Blood Metabolites and Autism Spectrum Disorder Risk: A Bidirectional Mendelian Randomization Study

Yulong Tian, Suya Ma, Wenhua Li
1 links
Health Science Reports
Autism Spectrum Disorder Research
article

Exploring the Association Between Human Blood Metabolites and Autism Spectrum Disorder Risk: A Bidirectional Mendelian Randomization Study

Yulong Tian, Suya Ma, Wenhua Li
article en

Abstract

Our findings indicate that the dodecenedioate, methionine sulfone, cysteine to alanine ratio and proline to glutamate ratio have an impact on ASD. These results enhance our understanding of the metabolic pathways involved in ASD and could lead to new avenues for intervention and prevention. Further research is needed to explore the mechanisms underlying these associations and confirm these findings in different populations.

Health Science ReportsVol. 8(3)
Tianjin University of Traditional Chinese Medicine (CN), Guang’anmen Hospital (CN)
Good health and well-being
Openalex Percentile: Top 96%
Autism Spectrum Disorder Research
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