Effect of alirocumab on postprandial hyperlipidaemia in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled, cross‐over trial

Inhibition of PCSK9 by alirocumab did not reduce PPL in T2D, confirming that PCSK9 controls remnant cholesterol catabolism rather than intestinal chylomicron production.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2025-03-05
DOI
https://doi.org/10.1111/dom.16305
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Effect of alirocumab on postprandial hyperlipidaemia in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled, cross‐over trial

Bertrand Cariou, Arsênio Rodrigues Oliveira, Béatrice Guyomarch, Claire Cannet et al.
Diabetes Obesity and Metabolism
Lipoproteins and Cardiovascular Health
article

Effect of alirocumab on postprandial hyperlipidaemia in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled, cross‐over trial

Bertrand Cariou, Arsênio Rodrigues Oliveira, Béatrice Guyomarch, Claire Cannet, Maxime Carpentier, Pierre Morcel, Patrick Giraudeau, Mikaël Croyal, Audrey Ernould, An Thys, Cédric Le May, Laurent Flet, Marine P. M. Letertre, Samy Hadjadj
article en

Abstract

Inhibition of PCSK9 by alirocumab did not reduce PPL in T2D, confirming that PCSK9 controls remnant cholesterol catabolism rather than intestinal chylomicron production.

Diabetes Obesity and MetabolismVol. 27(6)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Centre Hospitalier Universitaire de Nantes (FR), Chimie et Interdisciplinarité, Synthèse, Analyse, Modélisation (FR), Bruker (Germany) (DE), Institut du Thorax (FR), Nantes Université (FR)
Good health and well-being
Openalex Percentile: Top 93%
Lipoproteins and Cardiovascular Health
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