Prevalence and Risk Factors of L‐Asparaginase‐Related Thrombosis Among Acute Lymphoblastic Lymphoma Patients in a Resource‐Limited Setup of Sub‐Saharan Region

This study showed that the risk of L-asparaginase-associated thrombosis in resource-limited settings like ours is comparable with previous reports from other parts of the world, but the mortality directly attributed to thrombosis is remarkably higher. Older age above 40 years and longer time to achieve CR are independent predictors of higher thrombosis risk. Future prospective studies need to look into the contributing factors, and preventive and treatment strategies.

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Publication Details

Journal
Cancer Reports
Published
2025-03-01
DOI
https://doi.org/10.1002/cnr2.70153
Citations
2
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
3.76
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article

Prevalence and Risk Factors of L‐Asparaginase‐Related Thrombosis Among Acute Lymphoblastic Lymphoma Patients in a Resource‐Limited Setup of Sub‐Saharan Region

Fozia Abdela, Abel Tenaw Tasamma, Mahlet Tsige Weldeamanuel, Ameer Mohammed et al.
2 citations
Cancer Reports
Acute Lymphoblastic Leukemia research
3.76
article

Prevalence and Risk Factors of L‐Asparaginase‐Related Thrombosis Among Acute Lymphoblastic Lymphoma Patients in a Resource‐Limited Setup of Sub‐Saharan Region

Fozia Abdela, Abel Tenaw Tasamma, Mahlet Tsige Weldeamanuel, Ameer Mohammed, Yemisrach Kifle Shewangizaw
article en
2 citations

Abstract

This study showed that the risk of L-asparaginase-associated thrombosis in resource-limited settings like ours is comparable with previous reports from other parts of the world, but the mortality directly attributed to thrombosis is remarkably higher. Older age above 40 years and longer time to achieve CR are independent predictors of higher thrombosis risk. Future prospective studies need to look into the contributing factors, and preventive and treatment strategies.

Cancer ReportsVol. 8(3)
Addis Ababa University (ET)
Good health and well-being
Openalex Percentile: Top 9%
Acute Lymphoblastic Leukemia research
3.76
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